Hexarelin: Growth Hormone Releasing Peptide

Hexarelin: Growth Hormone Releasing Peptide

Hexarelin is a part of the GHRP family of peptides that act on the pituitary gland and the hypothalamus to release Human Growth Hormone (HGH). The various GHRP (or Growth Hormone Releasing Peptides) were discovered in the 1990’s and since then have been subjected to extensive clinical research.

GHRPs such as GHRP-2, GHRP-6, Ipamorelin and Hexarelin stimulate the pituitary gland to produce endogenous Growth Hormone (or GH). They are all similar drugs with a similar action. Among all the GHRPs, Hexarelin is the strongest. It is known to produce a powerful GH secretion. It is also known to increase cortisol and prolactin level.

Hexarelin is the recommended medication for GH deficiency.  Hexarelin is quite popular with professional athletes as a performance enhancement drug. One of the major advantages of taking Hexarelin, compared to other GHRPs such as GHRP-2 and GHRP-6 is that it does not lead to an automatic increase in appetite. This is because Hexarelin does not increase the Gherelin levels by any great extent. Ghrelin is, of course, responsible for increased hunger and faster gastric emptying.

 Let’s see what are the main benefits of taking Hexarelin.

Ø It builds up physical strength and stamina

Ø It stimulates the growth of new muscle fibers

Ø It speeds up the growth the muscle fibers that are already in the body

Ø It offers excellent protection to the body’s joints

Ø It helps to reduce the amount of fat in the body

Ø It makes the skin more elastic

Ø It increases bone density

Ø It helps to recover faster from injuries

How Does Hexarelin Work?

The application of Hexarelin into the body leads to several natural functions. First, Hexareline circulates the growth hormones in the body. It stimulates the secretion of IGF-1 by the liver. IGF-1 means Insulin like Growth Factor. An increase in IGF-1 stimulates faster muscle growth.

Hexarelin is quite the same as GHRP-6 structurally, but does not induce hunger like GHRP-6 does. Hexarelin helps to reduce the amount of fat in adipose tissues. Hexarelin helps protect neural activity in the central nervous system as well.

Who Uses Hexarelin?

Hexarelin is recommended to those who are deficient in the Growth Hormone. It is taken by older men and women to slow down the aging process. Athletes are the most common users of Hexarelin because of how it helps with fat loss and muscle growth. It is taken by men and women who wish to lose weight fast as well. Hexarelin makes the skin more elastic, which is why it is popular with those looking for a younger looking skin. Hexarelin is also taken by bodybuilders who are looking to shed fat and gain muscle mass.

How to take Hexarelin?

Hexarelin should be taken 1 to 3 times a day, and no more than that.  If you are taking Hexarelin for fat reduction or muscle gain, you may have it two to three times a day. If you’re taking it for other reasons, such as to slow down aging or to make the skin more elastic, you shouldn’t take Hexarelin more than once a day. Hexarelin should be taken in the form of subcutaneous injections, but never on an empty stomach. It should be injected directly under the skin into the stomach, thighs, or buttocks, or into the biceps and shoulders.

What are the side effects of Hexarelin?

Hexarelin is a powerful peptide, not as mild as other GHRPs such as Ipamorelin. Hexarelin must be taken well within its recommended dosage, otherwise it could cause water retention, tightness in the muscles, or even carpal tunnel-like symptoms. It may also cause numbness and tingling in the extremities, a decrease in insulin sensitivity and exhaustion. However, none of the Hexarelin side effects are as severe as those caused by the intake of synthetic Human Growth Hormone.

GHRP-2 and the Fountain of Youth

GHRP-2

GHRP-2 belong to a family of peptides that were discovered back in the 1990’s as synthetic tissue derived amino acids.  GHRPs such as GHRP-2 act at the pituitary and the hypothalamus to release the Human Growth Hormone (HGH) by activating a G protein-coupled receptor.

In most clinical studies, GHRP-2 was found to be the most powerful GHRP that stimulated the pituitary glands’ natural production of HGH. GHRP-2 was found to boost the hypothalamus function as well.

A GHRP-2 therapy, that releases Human Growth Hormones (HGH), is one of the most effective ways of slowing down the process of aging in adult men and women.

Let’s look at some of the benefits of GHRP-2:

Ø It cuts down belly fat through lipolysis

Ø It increases the sex drive by stimulating the hypothalamus

Ø It improves protein synthesis

Ø It improves eyesight and vision

Ø It reduces liver uptake of glucose, which is the opposite of what insulin does

Ø It boosts energy and vitality

Ø It helps to improve the skin elasticity and reduces wrinkles

Ø It makes the heart stronger and healthier

Ø It makes the immune system stronger

Ø It boosts stamina and increases endurance

Ø It speeds up the recovery from wounds or surgery

Ø It boosts the IGF-1 production by around 50% in the first week of use itself

Ø It helps you get good, sound sleep

Ø It increases your calcium retention, improves bone density and strengthens and enhances the mineralization of bone

Ø It helps with liver glucogenesis

Ø It helps improve the functionality of the pancreatic islets

There have been several clinical studies, such as one published in the Journal of Endocrinology and Metabolism in 1997 that show how a medically supervised therapy involving GHRP-2 increased growth hormone levels in both adults and children, and helped addressed issues related to growth hormone deficiency. It was found that the GHRP-2 therapy led to an increase in the body’s growth hormone, because of much higher IGF-1 levels. This has an anabolic effect on the tissues as well as several other benefits, as listed above.

How does GHRP-2 Work?

GHRP-2 activates the pituitary gland, which results in an increase in the production of the endogenous growth hormone. GHRP-2 enhances the body’s growth hormone naturally, without any of the side effects associated with synthetic hormone use.

GHRP-2 boosts HGH production in a two-step process:

Ø By boosting the growth hormone through an amplification of the transduction pathway which releases a hormone signal.

Ø By suppressing somatostatin, which results in an increase in the endogenous growth hormone levels.

GHRP-2 has to be administered daily, though subcutaneous injections, orally or by an intra-nasal route. For enhanced effect, GHRP-2 has to be used in conjunction with GHRP-6 and Sermorelin, which perform an action similar to it, which is to activate the pituitary gland to manufacture higher natural human growth hormone. This aids the functionality of the hypothalamus as well.

How Safe is GHRP-2?

GHRP-2 is considered to be a safe alternate to synthetic Human Growth Hormone, and it has been tested in several clinical trials. HGRP-2 has been approved by a number of scientists. What is important is to take GHRP-2 within the suggested dose, strictly adhering to your doctor’s advice. It is very important not to take GHRP-2 excessively as that might lead to side effects such as water retention, exhaustion or numbness and tingling in the extremities. GHRP-2 is certainly a better alternative to synthetic Human Growth Hormone (HGH) which is known to have too many side-effects.

Ipamorelin: Growth Hormone Releasing Peptide of the Future

Ipamorelin: Growth Hormone Releasing Peptide of the Future

Ipamorelin

Ipamorelin is the latest muscle building peptide supplement recommended for bodybuilders and professional athletes. Ipamorelin belongs to the family of peptides known as GHRPs, that are known to act on the pituitary gland and stimulate the production of the Human Growth Hormone – which is essential for muscle growth.

Ipamorelin is the cleanest, safest and the most versatile GHRP out there. It is very similar to another GHRP called Hexarelin, but much milder. It performs the same action as GHRP-2 and GHRP-6, but without their side effects such as a spike in appetite. The GH (Growth Hormone) released by Ipamorelin is known to be particularly potent and effective for muscle gains and weight loss.

Many clinical tests have been done on Ipamorelin, and so far the peptide appears to be safe, with a pronounced effect on weight loss and muscle gain. The Growth Hormones released by Ipamorelin help with faster muscle growth, while avoiding bone or cartilage distortions.

Let’s look at some of the benefits associated with Ipamorelin.

Boosts Growth Hormone levels in the body

Ipamorelin is one of the best promoters of Human Growth Hormone in the market and stimulates the production of HGH naturally. It works by binding itself to the G protein-receptors in a cell and triggers release of HGH.

Reduces Appetite, Unlike Other Peptides

Ipamorelin is different from other peptides in the GHRP family because it does not raise hunger levels significantly. It increases the growth of muscle and reduces body fat. With Ipamorelin, you can stick to your diet without having to suffer from hunger pangs.

 Increases the Body Weight the Healthy Way

How does it Work?

Ipamorelin is recommended to those looking to gain body weight, but the healthy way. With Ipamorelin, you will gain in muscle mass, not body fat. While studying the effects of Ipamorelin, scientists tested the peptide on rats. It was found that it led to an increase in body weight of the rats, along with a faster muscle growth with zero bone deformity risk.

When you inject Ipamorelin into the body, a pulse is generated that stimulates the pituitary gland or the hypothalamus, causing the release of GH.  This pulse endures for 3 hours following the injection of Ipamorelin. Once the pulse is sent, the cells go directly into the development of muscle while staying away from any bone or cartilage growth. So there is no likelihood of a bone deformity happening when you take Ipamorelin. For this reason, Ipamorelin is preferable to synthetic HGH, which is known to cause swelling of the joints. Ipamorelin causes fat loss, provides much needed nutrition and builds clean muscle mass.

How to take Ipamorelin?

It should be administered by a subcutaneous injection, no more than two or three times a day. It can be injected in the stomach, buttocks or any fleshy part of the body. Ipamorelin should be stored in a cool, dry place such as a refrigerator.

Are there any Ipamorelin Sides Effects?

Ipamorelin is actually the mildest and safest of all peptides in the GHRP family and has no serious side effects. However, high doses of Ipamorelin can increase cortisol or acetylcholine levels. This may cause simple side effects such a slight dizziness or minor headaches, when Ipamorelin is taken in excess.  Ideally, Ipamorelin should be taken 45 minutes before a workout.  

More information on GHRPs:  http://www.knightpeptide.com/2015/06/growth-hormone-releasing-peptides-or.html

GHRP-6 - New Advances in HGH Stimulation

GHRP-6

In many clinical tests, GHRP-6 has been found to be very effective at stimulating the pituitary glands’ natural production of HGH. It is an injectable peptide which falls in the category of GHRPs or growth hormone releasing peptides.

GHRPs are peptides that were discovered 20 years ago as synthetic tissue derived amino acids.  GHRPs act on the pituitary and the hypothalamus, and activate a G protein-coupled receptor, which results in the release of the Human Growth Hormone (HGH).

All GHRPs, including GHRP-6 work to produce Human Growth Hormone naturally.  GHRP-6 can be used alone or in a combination with other peptides in this category, such as GHRP-2, Hexarelin, and Ipamorelin. All GHRPs are similar in properties and functionality.

GHRP-6 increases the Growth Hormone levels, which leads to an increase in the IGF-1 level. This helps with faster fat loss and with muscle gains as well. GHRP-6 is used as a safer alternative to synthetic Growth Hormones. It is known to increase appetite, reduces inflammation, and helps one recover faster from injuries.

Who may benefit from GHRP-6?

GHRP should be taken by:

Ø Bodybuilders -Perfect for bodybuilders who are looking to get bigger and build muscle mass

Ø Dieters - Ideal for those who are looking to shed body fat

Ø Seniors- Considered beneficial to older people because of its anti-aging benefits

Let’s look at some of the benefits of taking GHRP-6.

Ø Impressive gains in muscle mass

Ø More strength and stamina

Ø Shedding of body fat

Ø Greater bone density and better bone tissue growth

Ø Helps with the production of IGF-1 by the liver, which results in faster loss of fat

Ø It slows down the process of aging.

Ø Boosts immune response

Ø Builds up strength in the joints, connective tissue, and body mass

Ø Known to inhibit Ghrelin, which is known to cause weight gain and insulin resistance

When would be proper dosing of GHRP-6?

GHRP-2 should be taken for the same purpose for which you may want to take GH for. But it is preferable to take GHRP-6 when GH is not available, or when you would rather have your body stimulate GH on its own than inject GH artificially. GHRP-6 may be used in a combination with anabolic steroids for massive muscle gains and faster recovery from injury. When taking GHRP-6 as a part of a fat loss program, it is recommended to stick to the minimum dosage, as far as possible. You may take GHRP-6 in combination with other GHRPs or with GH for maximum benefit.

How much GHRP-6 should you take?

GHRP-6 should be taken 1 to 3 times a day, based on your goals. If you are taking GHRP-6 for fat reduction or muscle gain, you should take it thrice a day, and if you’re taking it for its anti-aging properties, you shouldn’t take GHRP-6 more than once a day. GHRP-6 would be taken as injections, but never on an empty stomach. It would be applied directly under the skin into the stomach, thighs, or buttocks, or into the biceps and shoulders.

What are the Side Effects of GHRP-6?

GHRP-6 has no serious side effects. It does cause an increase in appetite, which you should guard against. Otherwise, GHRP-6 is perfectly safe, and a much better alternative to synthetic GH, which is known to have many harmful side effects.

Thymosin Beta-4; An Effective Way To Get Rid Of Muscles Pain

Thymosin Beta-4; An Effective Way To Get Rid Of Muscles Pain

In the thymus, a unique peptide has been discovered that is known as Thymosin Beta-4 or TB-500. This is the human body gland that since its invention Thymosin Beta-4 has been found in the tissues of the whole body of human beings. This is the main interest that connect with muscles. In the case, damage can occur in muscles tissues Thymosin Beta-4 is the beneficial term that healing of trauma. Moreover, next version of Beta-4 is TB500 that do wonderful things naturally and you should claim by marks some key points that are under as:

• Cell variation
• Dermal tissues that helpful to growth of new cells
• Migration of Keratinocyte
• Deposition of Collagen
• Inflammation Decreases
With the regard of these intentions, there are many good things that decrease inflammation. This is strong like the horses.
Thymosin Beta-4 benefits:
It is different from other fix aspects because it encourages endothelial and keratinocyte migration. It also does not combine to the extra-cellular matrix and has a very low molecular weight. Because of this, it can journey long ranges through the cells in the human body.
If you got shoulder pain, this is effective products that will easy stay off your pain. This is a typical dose that obtains for that people who should avoid the stress of muscle issues. This is engaged in controlling the defense mechanisms. Improving stages of Thymosin through the use of the medication successfully reduces the body’s inflammation related reaction to damage, because the damage would then be treatment at a much quicker rate. It is also recommended amongst medical types Thymosin has a common part in cells regrowth.
It knows what creators of it are offering for pets and horses. Improved stamina, muscle durability, versatility, less scarring damage, and reduced inflammation. Hence, are there any advantages for humans? Some researchers think it may be able to help our minds and hearts cure after cardiac arrest. I have seen one research display that Thymosin Beta-4 triggers progenitor tissues after cardiac arrest, basically enabling the center to cure itself. I have also studied somewhere else that this impact has not been duplicated during further examining. The last one, in particular, should create a lot of feelings. Thymosin Beta-4 is engaged in controlling the defense mechanisms. Improving stages of Thymosin Beta-4 through the use of TB-500 would reduce our information related the reaction to damage because the damage would be treatment at a much quicker amount. Swelling is our body’s indication to fix. Once that fix is ongoing, inflammation goes down.
How to use?
It will be used for four to six weeks that called slandered dosing. An average dose is three mg on every day. This is a lower dose that will never effect on your body. Thymosin Beta-4 is a protein which includes 43 portions of meat and is secured by the gene TMSB4X in the human body. It has been researched in several scientific tests. Research has revealed that if the thymosin beta-4 peptides are used after heart arrest, it can resume heart progenitor cells to fix broken center cells.

Growth Hormone Releasing Peptides or GHRPs

Growth Hormone Releasing Peptides or GHRPs

Growth Hormone Releasing Peptides, commonly known as GHRPs, are not approved for human use by the FDA and therefore should only be used in a research atmosphere by qualified professionals.  Despite this many bodybuilders in the modern world seek the assistance of growth hormone releasing peptides. These peptides have the ability to let them experience a boost in appetite about 20 minutes after the injection. A single pulse will last for around 30 minutes and another one will not be generated for the next three hours.

What are the different types of Growth hormone release peptides that can be found out there?

The available growth hormone release peptides can be divided into four major categories. They are:

·         Ipamorelin – Ipamorelin is the gentlest growth hormone releasing peptide that can be found. It does not have the ability to increase prolactin or cortisol level at any dose.

·         GHRP-6 – This is one of the more potent and effecting growth hormone releasing peptides available for the modern world. GHRP-6's affect on prolactin or cortisol level is very dose dependent.  

·         GHRP-2 - GHRP-2 is slightly more potent when compared to GHRP-6. It can also deliver a stronger effect to your hormones at all dosage levels. In other words, GHRP-2 gives life to a high normal range of prolactin or cortisol.

·         Hexarelin – Hexarelin is slightly harsher than GHRP-2 and it can be considered as the strongest growth hormone release peptide out of the list. Therefore, Hexarelin can deliver the strongest impact on prolactin and cortisol levels at all dosage levels.

All these growth hormone releasing peptides can get desensitized by having a constant usage throughout the entire day. However, you should note that GHRP-6 and Ipamorelin do not desensitize when there are short breaks in between. The highest potency GHRP, Hexarelin desensitize without any regard to the dosage. Therefore, research has shown test subjects experience its effect for a period of 14 days.

Can GHRPs be used alone?

Yes. GHRPs can create larger pulse of growth hormone on their own when compared to growth hormone releasing hormones. This is done with enhanced predictability and consistency. Therefore, GHRPs are often used alone in research protocols.

What is the typical protocol for GHRH?

From the studies, it has been identified that the typical conversion of protocol would be around 5 to 7 days a week with subcutaneous injections. Typical dosage of approximately 100 to 200mcg of it per one dose.  The number of intakes per day is sometimes increased in order to test increased effectiveness.

No adverse effects have been reported with the continuous usage of growth hormone release peptides.  The results delivered by GHRPs are effective and they have the ability to deliver long lasting results to the users without much hassle.  Many people are encouraged by the results of the studies and research performed using GHRPs and look forward to increased research into these peptides.