PT-141 (Bremelanotide)
PT-141 (or Bremelanotide) which is developed from Melanotan II, is a new drug which treats sexual dysfunction in both men and women. PT-141 and Melanotan II are said to be true aphrodisiacs, in the classical sense of the term.
Melanotan II is an
artificially produced variant of a peptide hormone that stimulates
melanogenesis, known as the alpha-Melanocyte stimulating hormone.
PT-141 has picked up the
reputation of being the only effective synthetic aphrodisiac in the market. Many
clinical trials have been done that show how PT-141 can be an effective cure
for men suffering from sexual dysfunctions such as Erectile Dysfunction and
impotence. It has wonderful benefits for women as well, as it is believed to
have the potential to cure sexual arousal disorder, which affects many women.
Drugs such as Viagra, Levitra
and Cials are not exactly aphrodisiacs; they don’t have a direct effect on the
libido. PT-141 is an aphrodisiac and helps with the libido. It can have a
synergistic effect if used in a combination with PDE5 inhibitors.
PT-141 is based on
Bremelanotide, a known aphrodisiac. Bremelanotide is a melanocortin peptide
hormone. It binds itself to the melanocortin 4 receptor in the brain, which
causes sexual arousal in women. 90% of the participants in various tests have
claimed to experience a strong sexual arousal.
What PT-141 does is to target
the brain’s arousal center. In some of the initial tests done on lab rats, it
was found that administering PT-141 in female rats threw them into a state of
extreme sexual arousal, so much that they became sexually aggressive with the
males.
Can PT-141 cause instant
sexual arousal in women with low libido, who are generally indifferent to
sexual desires? Well, scientists working at Palatin Technologies say that a
nasal spray with PT-141 used by them sent female participants in the trials
into a state of high sexual arousal.
In around three years,
Palatin Technologies hopes to sell PT-141 to the public, to treat men and women
with sexual issues - impotence and ED in men and low sexual arousal in women.
This is of a particular
benefit to women. It is believed that 40% of women have issues with sexual
arousal – while they are interested in sex, they find it hard to reach climax.
This could also be the answer many men are looking for, as nobody likes having
a partner who is not sexually aroused by you. Could PT-141 be the magical glue
that saves marriages around the world?
In another study conducted at
the New Jersey's University of Medicine and Dentistry, of the 32 healthy female
participants, 16 were given PT-141 and 16 were given a placebo. All women were
shown videos with sexual content and had detectors on them that measured the blood
flow in their sexual organs.
The women on placebos showed
no great reaction, but women on PT-141 had great increases in the blood flow.
So, clearly, this is a drug that works as a true aphrodisiac and helps women
with their arousal problems. For PT-141 to really work, the woman has to have
at least some intention of having sex with a man – it cannot make a woman who
has no interest in a man suddenly want to have sex with him. The woman has to
be half-way there already if PT-141is to be effective.
So far PT-141 can only be had
as a nasal spray and injection. It is hoped that it can be had as pills in the
future, which is obviously a more convenient way of taking a drug.
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