Melanotan II – The Tanning Peptide

Melanotan II - The Tanning Peptide

Why Buy Melanotan II?

Melanotan II is a synthetic drug replicates the performance of the alpha-melanocyte stimulating hormone. It is explicitly used for tanning, but has other benefits as well. Melanotan II boosts the sex drive and is a cure for erectile dysfunction. Melanotan 2 can be had as a subcutaneous injection. It is available in as an inhaler too, but Melanotan’s effectiveness in any form other than as an injection is in doubt. Melanotan II should not be confused with Melanotan ii, which is a completely different compound.

How Does Melanotan II Work?

Melanotan II was originally developed to prevent skin cancer. Since then it has found quite a few uses, and is used widely by bodybuilders for tanning. Bodybuilders love the tans they get from taking Melanotan II, and none of the regulatory bodies have an issue with this.

Melanotan 2 works by copying the effects the body’s melanin cycle. Melanin is triggered naturally by the alpha-melanin stimulating hormone, which initiates the process of melanogenesis. After a lot of research scientists were able to create a peptide that had over hundred times the potency of the alpha-melanin stimulating hormone, which could create tanning naturally without having to spend hours in the sunlight getting exposed to UV radiation –which they named Melanotan II, popularly known as the “tanning peptide”.

Melanotan II - the Tanning Peptide

One great reason to buy Melanotan 2 is that it is a very flexible compound. You can take it at a pace you are comfortable with. You can start off slow, with just 0.25 mg of Melanotan and gradually build up the dosage with time, as you observe how well the tan develops.

It’s perfectly okay to increase the dosage up to 1 mg, and up to 2 mg, but never more than that. You can inject Melanotan 2 by a subcutaneous injection by applying it into a fleshy part of the body, such as the buttocks, shoulders, stomach or thighs.

You should not feel any pain from the injection, but if you do, you should stop immediately. Melanotan 2 gets you a tan very quickly. Of course, how long the tan takes to appear varies from person to person.

One big reason to buy Melanotan 2 is that you don’t really have to take it for too long. The tanning happens fast and you can quit taking the peptide regularly once it appears. You only have to take it once every 2 or 3 weeks to maintain the tan. The tanning peptide is so powerful that your tan remains even without much exposure to sunlight, even after you stop taking it. A natural tan, for example, would disappear within a month of staying away from sunlight.

Melanotan 2 and Erectile Dysfunction…

Melanotan 2 cures erectile dysfunction and boosts libido in men. For this to work, it should be taken 6 hours before the sexual intercourse. It helps with the erection of the penis when aroused. The effects of Melanotan linger on, for 6 to 12 hours after taking it. No more than 2 mg of Melanotan 2 should be injected into the body in preparation for the intercourse.

The Healthy Way to Tan - Melanotan 2

Why Should You Buy Melanotan II?

Melanotan 2 or the “tanning peptide” has become a global phenomenon because of how effective and safe it is for people looking to get tanned quickly. Melanotan II is popular for giving people a sunless tan as those who take it don’t have to stay out in the sun for too long and expose themselves to a UV radiation in order to get a tan. It lowers the risk of getting sun burns or skin cancer for this reason.

Melanotan and Melanotan 2

It was the University of Arizona that first developed a new way to tan, creating a peptide that worked in the same manner as the skin pigment, melanin did. The new drug was named Melanotan, and soon after a more powerful version of the drug was developed, which was called Melanotan 2. You may want to have a look at some of the before and after pictures online that show you just how powerful Melanotan II can be as a tanning substance.
Melanotan II is very popular in salons across the country, in the bodybuilding community and with the general public. Melanotan 2 is created in labs across the world, especially in China, Australia and the United States. A lot of people are seeing the benefits of taking this very useful drug. To understand why Melanotan 2 is so popular, let’s understand why people tan in the first place.

So, why do people tan?

People tan for various reasons – to feel sexier and more attractive to the opposite sex, to look good and to build confidence. Bodybuilders tan as this helps to accentuate their muscles in a bodybuilding contest. Tanning takes away the pale and sickly look and makes you feel young, healthy and strong.

How NOT to tan?

You shouldn’t tan by exposing yourself for hours to direct sunlight and UV radiation. UV radiation causes the skin to produce melanin. Melanin darkens the skin and protects it from further exposure to UV radiation. As the skin gets exposed further, it produces more melanin, which causes the skin to tan. The same method is used in tanning beds where the tanning is done even faster, with further damage inflicted. Prolonged exposure to the sunlight or overuse of tanning beds has been linked to skin diseases such as melanoma and skin cancers.

Why UV is not always bad

UV light is not always bad as long as the exposure is controlled. Many of the important vitamins and hormones the body produces are as a result of exposure to UV radiation. A certain amount of exposure to UV radiation is important and even healthy. Staying away from sunlight for too long would put you at the risk of vitamin D deficiency. That’s why when you take Melanotan 2, you are required to have at least some exposure to sunlight for the drug to work. But this exposure is really quite minimal. The point is, you need the sun, but not a sun burn!

Melanotan 2 – The Healthy Way to Tan

Melanotan II is the most effective way to tan. It has been described as the future of tanning. There are no serious side effects of taking this peptide, other than a slight darkening of existing freckles or nausea. It acts fast and produces the tan very quickly, with little effort. It is a painless way to tan and makes you look good in no time at all.

Melanotan II Can Do More Than Tan

Melanotan II Can Do More Than Tan

After the discovery of a naturally-occurring peptide that stimulates melatonin production (which was unimaginatively named "Alpha-melanocyte-stimulating hormone"), scientists swiftly became excited by the possibilities. Here was a chemical that could tan skin without the risks associated with tanning beds (i.e. Increased risks of skin cancer like Melanoma)!

Then when researchers at the University of Arizona were able to synthesize an artificial version of the peptide, in fact, it was introduced as a way to prevent the formation of skin cancer in susceptible individuals. Dubbed "Melanotan" (followed by the improved "Melanotan II"), this compound was found to be more stable than the natural peptide and 1,000 times more effective!

But early clinical trials swiftly demonstrated that, for better or worse, Melanotan does much more than tan!

Uckert, Bannowsky, Albrecht, and Kuczyk (2014) found that melanocortin receptor agonists like Melanotan II are highly effective at activating the central melanocortin system involved in both male and female sexual function. For this reason Melanotan II has been reported as having “aphrodisiac” effects. This effect was discovered accidentally when initial male subjects in sunless tanning trials reported spontaneous penile erections. Several follow-up studies have determined that Melanotan II seems to be an effective treatment for male erectile dysfunction (physical or psychological) as well as female arousal and orgasm disorders.

If such a versatile and effective aphrodisiac turns out to truly be safe for human use, it could well become the most commercially viable drug of all time! Throughout history, people have always gone nuts for aphrodisiacs, whether or not they were effective. Often substances marketed as "aphrodisiacs" were ineffective and marketed on superstition more than anything, but for Melanotan, "aphrodisiac" seems to be an understatement! Just think of all the rhinos and deer that would still have their horns, all the goats and tigers that would still have their penises if effective medicinal cures were discovered earlier! Melanotan’s aphrodisiacal properties have given even more cause for excitement than its original function as a sun-less tanning agent.

Preliminary studies on mice (Rinne et. Al. 2014) found that Melanotan II can even be an effective therapy for atherosclerosis. The Melanotan II peptide treatments not only limited plaque inflammation in mice, but also improved vascular endothelial function.

Another study (Xu et. Al. 2014) found that Melanotan II had profound effects on metabolism: when administered intraperitonally it swiftly decreased body temperature and energy expenditure. Again it shows potent medical applications (e.g. As a fever reducer), but it is obviously not a compound to be taken lightly!

It seems that the effects of Melanotan II vary based on where it is applied and the course of treatment. While it was originally synthesized to increase melanin production, it's full impact on health and vigor may be MUCH greater. While Melanotan II is still in an experimental stage, and scientists are still trying to determine its health effects, its multiple applications make it an unusually promising substance to research, and hence a substance that's value is likely to skyrocket if and when it becomes approved for human use.

Rinne P¹, Silvola JM², Hellberg S², Ståhle M², Liljenbäck H², Salomäki H², Koskinen E², Nuutinen S², Saukko P², Knuuti J², Saraste A², Roivainen A², Savontaus E² (Jul 2014). “Pharmacological activation of the melanocortin system limits plaque inflammation and ameliorates vascular dysfunction in atherosclerotic mice.” Arterioscler Thromb Vasc Biol. PMID: 24790139.

Uckert S1, Bannowsky A, Albrecht K, Kuczyk MA (Nov. 2014). “Melanocortin receptor agonists in the treatment of male and female sexual dysfunctions: results from basic research and clinical studies.” Expert Opin Investig Drugs.  PMID: 25096243.

Xu Y., Kim ER., Fan S, Xia Y., Xu Y., Huang C., Tong Q (Aug 2014). "Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists." Biochem Biophys Res Commun. PMID: 25065745.

Does Melanotan II Work?

Melanotan II (or MT2)

Melanotan II or MT2 is popularly known as the tanning peptide and it should not be confused with Melanotan ii, which is entirely different. Melanotan II or MT2 is taken by athletes and bodybuilders for faster tanning, suppression of appetite and increasing the libido. Taking MT2 ensures that you get a tan with as little exposure to UV radiation as possible this makes it, by far, the most effective tanning peptide in the market.

MT2 stimulates the production of melanin, which helps provide a natural tan to the body, and darkens the skin slightly to protect it as much as possible. You should never expose yourself to UV radiation just to get a tan as it may lead to skin cancer and other health issues.

What are the Benefits of MT2?

MT2 helps men with erectile dysfunction and other issues related to sexual performance.

While MT2 does require exposure to UV radiation to produce a tanning effect, taking it ensures that the exposure can be limited to as little time as possible.

You can be very flexible with your dosage of MT2 – there are no set rules. You can, for instance, start off with a small dosage and gradually build it up after a week or so, if you’re satisfied with the effects of the peptide.

The tan produced by MT2 does not go away just because you stop taking the peptide. It lasts for months, even without exposure to sunlight. A tan that is produced naturally on the other hand, fades away in a month’s time.

How to take Melanotan II?

MT2 helps people who are very fair develop a tan easily. It is of a particular benefit to those with pale skin and who are at a risk of skin cancer. It also works in the brain to stimulate the erection of the penis. It has to be injected through an injection using sterile water, just under the skin.

For curing erectile dysfunction in men, MT2 should be injected just 4 to 6 hours before sexual intercourse and its effects can last for 6 to 12 hours after the injection. The recommended dosage is 0.5 to 1 mg. It should never over 2 mg.

For tanning skin, the recommended dosage is 0.025 mg. The injection is taken just once a day, and increased slightly to 0.5 to 1.0 mg per day, if found to be effective and without side effects.

What are the side effects of MT2?

The side effects of MT2 are increased growth of moles, nausea, stomach cramps, lack of appetite, exhaustion, flushing, yawning, darkened skin, unintended erections of the penis, and so on.

Never take Melanotan II if you’re pregnant or breastfeeding, and remember to consult with your physician first before getting started with it.

The Bottom Line

Melanotan II or MT2 serves two practical problems. One, it helps you get a tan without requiring too much exposure to UV radiation and the tan lasts for months. Two, it helps cure erectile dysfunction in men. But proper dosage protocol should be maintained while taking MT2.

Melanotan II (Melanotan 2)

Melanotan II (Melanotan 2)

Melanotan II is a synthetic analog of the naturally occurring melanocortin peptide hormone alpha-melanocyte stimulating hormone (a-MSH). This peptide was developed by the University of Arizona.  In preliminary studies and clinical trials it has been shown to have melanogenesis (tanning) and aphrodisiac effects.
Melanotan II was developed at the University of Arizona as a tool to prevent skin cancer.  The researchers understood that one of the best ways to prevent skin cancer was to have melanin activated in the skin.  This process is what causes a tan to the skin.  The researchers believed they could reduce the risk by triggering the body's natural pigmentation to tan before UV exposure.  In nature the UV exposure causes production of the hormone a-MSH.  This causes melanogenesis (tanning) by triggering the melanocytes (skin's pigment cells) to produce the skin pigment (melanin).  The researchers at the University of Arizona hypothesized that by introducing the a-MSH hormone directly into the body they could produce a sunless tan.  During initial studies this method appeared to show results.  However the short half life of naturally occurring a-MSH made it impractical to use as a therapeutic drug.
This led researchers headed by Victor J. Hruby and Mac E. Hadley to synthesize and study hundreds of molecules.  They eventually located a peptide, [Nle^4, D-Phe^7]-a-MSH, that was roughly 1,000 times more potent than naturally occurring a-MSH.  This new molecule peptide was named "Melanotan"; later Melanotan -1 and presently known as afamelanotide.  The researchers then developed another analog, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2.  This peptide molecule was named Melanotan II, also known as Melanotan 2 or MT2.  The scientists were hopeful these peptides could be used to prevent melanoma by stimulating pigment production without needing harmful exposure to UV radiation.  This would then reduce the amount of skin damage and lower to possibility of skin cancer potential.  
Pilot Phase 1 clinical trial was conducted on males in in Tucson at the University of Arizona and published in 1996.  The study published that they found Melanotan II promoted tanning activity in humans given only 5 low doses every other day by subcutaneous injection.  The reported side effects were mild nausea and a "stretching and yawning complex" that coincided with penile erections.  Since this study there have been numerous other studies conducted that also reported melanogenesis (tanning) and sexual arousal in both males and females.  These studies will be further explored in future articles.